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| Rodent model of Zoster-associated pain |
Background
Varicella-Zoster virus (VZV) is a neurotropic virus, which causes varicella (chickenpox) as the primary infection. Following the acute illness, the virus establishes latency within sensory ganglia in the peripheral nervous system (PNS). VZV may be reactiva…
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| Characterisation of mouse dorsal horn organisation |
| Our studies on how the CNS adapts and responds to different sensory modalities and duration of stimuli have important neurobiological implications, but in more general terms can also aid both the treatment of pain and the development of novel analgesics 1-3. The chal…
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| Cannabinoid signalling in the pain pathway |
| While the psychotropic and medicinal use of cannabis has been appreciated for millennia, it is only recently that endocannabinoids and their cognate receptors and synthesising and degrading enzymes have been identified. Because of its many similarities with the opioid s…
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