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Past Research
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Rodent model of Zoster-associated pain
Background
Varicella-Zoster virus (VZV) is a neurotropic virus, which causes varicella (chickenpox) as the primary infection. Following the acute illness, the virus establishes latency within sensory ganglia in the peripheral nervous system (PNS). VZV may be reactivated years later
Characterisation of mouse dorsal horn organisation
Our studies on how the CNS adapts and responds to different sensory modalities and duration of stimuli have important neurobiological implications, but in more general terms can also aid both the treatment of pain and the development of novel analgesics 1-3. The challenge is
Cannabinoid signalling in the pain pathway
While the psychotropic and medicinal use of cannabis has been appreciated for millennia, it is only recently that endocannabinoids and their cognate receptors and synthesising and degrading enzymes have been identified. Because of its many similarities with the opioid syst
The Functional Development of Supraspinal Pain Processing in the Human Neonate and Infant
The Fitzgerald research group has established the developmental pattern of neonatal acute pain responses and of primary and secondary hyperalgesia in human infants using spinal flexion withdrawal reflexes and abdominal skin reflexes. However little is known abou