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Wellcome Trust conference The Challenges of Chronic Pain

11-13 March 2015
Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Abstract deadline: 30 January 2015
Registration deadline: 16 February 2015

For more information
click here

News, Videos and Features News

Chronic pain: the search for a killer

Researchers engaging with local communities

Researchersí discovery of why sunburn hurts reveals possible target for new pain relief drugs

New award funding of LPC

UK researchers tackle pain

Imperial College and the London Pain Consortium partner with a Japanese chemical company to fight chronic pain

Videos

Walking on Fire click here

Features

London Pain Consortium: key Discoveries

Reserachers: Pain killers click here

Painstaking research - tackling chronic pain click here

The London Pain Consortium making a difference
Archive workshop and seminar slides Professor Peter Karmerman…
 
Publications
2013
Lana B, Schlick B, Martin S, Pratt WS, Page KM, Goncalves L, Rahman W, Dickenson AH, Bauer CS, Dolphin AC. Differential upregulation in DRG neurons of an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury. Pain. 2013 Dec 6 e pub

Lee MC, Tracey I. . Imaging pain: a potent means for investigating pain mechanisms in patients. Br J Anaesth. 2013 Jul;111(1):64-72

Lee MC, Wanigasekera V, Tracey I. Imaging opioid analgesia in the human brain and it's potential relevance for understanding opioid use in chronic pain. Neuropharmacology. 2013 Jul 25 e pub

Leknes S, Berna C, Lee MC, Snyder GD, Biele G, Tracey I. Response to the commentary "multiple potential mechanisms for context effects on pain". Pain. 2013 Aug;154(8):1485-6

Chen YC, Ayub M, Pristera A, Swanwick RS, Karu K, Hamada Y, Rice AS, Okuse K. Identification of a receptor for neuropeptide VGF and it's role in neuropathic pain. J Biol Chem. 2013 Oct 8 epub

Patel R, Bauer CS, Nieto-Rostro M, Margas W, Ferron L, Chaggar K, Crews K, Ramirez JD, Bennett DL, Schwartz A, Dickenson AH, Dolphin AC. Š2š-1 Gene Deletion Affects Somatosensory Neuron Function and Delays Mechanical Hypersensitivity in Response to Peripheral Nerve Damage. Journal of Neuroscience. 2013 Oct 16;33(42):16412-26

Perkins JR, Lees J, Antunes-Martins A, Diboun I, McMahon SB, Bennett DL, Orengo C. PainNetworks: A web-based resource for the visualisation of pain-related genes in the context of their network associations. Pain. 2013 Sep 11 e pub

Antunes-Martins A, Perkins J, Lees J, Hildebrandt T, Orengo C, Bennett DL. Systems biology approaches to finding novel pain mediators. Wiley interdisciplinary Review System Biology and Medicine. 2013 Jan-Feb;5(1):11-35 Review

Mancini F, Sambo CF, Ramirez JD, Bennett DL, Haggard P, Iannetti GD. A fovea for pain at the fingertips. Current Biology. 2013 Mar 18;23(6)496-500

Ellis A, Bennett DL. Neuroinflammation and the generation of neuropathic pain. British Journal of Anaesthesia. 2013 Jul;111(1):26-37

Stagg CJ, Lin RL, Mezue M, Segerdahl A, Kong Y, Xie J, Tracey I. Widespread modulation of cerebral perfusion induced during and after transcranial direct current stimulation applied to the left dorsolateral prefrontal cortex. Journal of Neuroscience. 2013 Jul 10;33(28):11425-31

Fricker FR, Antunes-Martins A, Galino J, Paramsothy R, La Russa F, Perkins J, Goldberg R, Brelstaff J, Zhu N, McMahon SB, Orengo C, Garrett AN, Birchmeier C, Bennett DLH. Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination. Brain. 2013 July;136(7):2279-2297 e pub 24 June

Denk F, Huang W, Sidders B, Bithell A, Crow M, Grist J, Sharma S, Ziemek D, Rice AS, Buckley NJ, McMahon SB. HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain. Pain. 2013 May 18. (epub ahead of print)

Paterson KJ, Zambreanu L, Bennett DL, McMahon SB. Characterisation and mechanisms of bradykinin-evoked pain in man using iontophoresis. Pain. 2013 Jun;154(6):782-92 E Pub 2013 Jan 11

Crow M, Denk F, McMahon SB. Genes and epigenetics processes as prospective pain targets. Genome Med. 2013 Feb 15;5(2):12 (epub ahead of print)

Eijkelkamp N, Linley JE, Torres JM, Bee L, Dickenson AH, Gringhuis M, Minett MS, Hong GS, Lee E, Oh U, Ishikawa Y, Zwartkuis FJ, Cox JJ, Wood JN. A role for Piezo2 in EPAC1-dependent mechanical allodynia. Nat Communications. 2013;4:1682

Sikander S, Patel R, Patel S, Sikander S, Bennett DL, Dickenson AH. Genes, molecules and patients-Emerging topics to guide clinical pain research. Eur J Pharmacol. 2013 Sep 15;716(1-3):188-202. (epub ahead of print)

Cregg R, Laguda B, Werdehausen R, Cox JJ, Linley JE, Ramirez JD, Bodi I, Markiewicz M, Howell KJ, Chen YC, Agnew K, Houlden H, Lunn MP, Bennett DL, Wood JN, Kinali M. Novel mutations mapping to the fourth sodium channel domain of nav1.7 result in variable clinical manifestations of primary erythromelalgia. Neuromolecular Med. 2013 Jun;15(2):265-78